Molecular weight (DA)
13kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
PDCD5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010],
Function
developmental stage:Expression in fetal tissues is significantly lower than in adult tissues.,function:May function in the process of apoptosis.,induction:Activated in cells undergoing apoptosis.,similarity:Belongs to the PDCD5 family.,tissue specificity:Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.,
Protein name
Programmed cell death protein 5 (TF-1 cell apoptosis-related protein 19) (Protein TFAR19)
Human protein sequence Database
O14737
Mouse protein sequence database
P56812
Rat protein sequence database
Cellular localization
nucleus,cytoplasm,cytosol,extracellular exosome,
Tissue expression
Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta.
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