Molecular weight (DA)
43kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SOX1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
SRY-box 1(SOX1) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008],
Function
function:Transcriptional activator.,similarity:Contains 1 HMG box DNA-binding domain.,tissue specificity:Mainly in the developing central nervous system.,
Protein name
Transcription factor SOX-1
Human protein sequence Database
O00570
Mouse protein sequence database
P53783
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Mainly expressed in the developing central nervous system.
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