Molecular weight (DA)
12kD
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity
MIEN1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May be involved in a redox-related process .,similarity:Belongs to the SelWTH family.,
Function
function:May be involved in a redox-related process .,similarity:Belongs to the SelWTH family.,
Gene Name
MIEN1 C17orf37 RDX12 XTP4
Protein name
Migration and invasion enhancer 1 (HBV X-transactivated gene 4 protein) (HBV XAg-transactivated protein 4) (Protein C35)
Human protein sequence Database
Q9BRT3
Mouse protein sequence database
Q9CQ86
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol. Cell membrane; Lipid-anchor; Cytoplasmic side. Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
Tissue expression
Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).