Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
RGMB Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr 2009],
Function
similarity:Belongs to the repulsive guidance molecule (RGM) family.,
Protein name
RGM domain family member B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON)
Fields
>>TGF-beta signaling pathway
Human protein sequence Database
Q6NW40
Mouse protein sequence database
Q7TQ33
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft .
Tissue expression
Placenta,Testis,