Molecular weight (DA)
104kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CCD80 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Promotes cell adhesion and matrix assembly.,induction:Down-regulated in cancer and after osteoblastic differentiation. Up-regulated by dihydrotestosterone (DHT).,PTM:Phosphorylated.,similarity:Belongs to the CCDC80 family.,subunit:Binds to various extracellular matrix proteins.,tissue specificity:Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.,
Function
function:Promotes cell adhesion and matrix assembly.,induction:Down-regulated in cancer and after osteoblastic differentiation. Up-regulated by dihydrotestosterone (DHT).,PTM:Phosphorylated.,similarity:Belongs to the CCDC80 family.,subunit:Binds to various extracellular matrix proteins.,tissue specificity:Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.,
Gene Name
CCDC80 DRO1 URB HBE245
Protein name
Coiled-coil domain-containing protein 80 (Down-regulated by oncogenes protein 1) (Up-regulated in BRS-3 deficient mouse homolog)
Human protein sequence Database
Q76M96
Mouse protein sequence database
Q8R2G6
Rat protein sequence database
Q6QD51
Cellular localization
Secreted, extracellular space, extracellular matrix .
Tissue expression
Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.
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