Molecular weight (DA)
54kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ANGL2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008],
Function
function:Induces sprouting in endothelial cells through an autocrine and paracrine action.,PTM:N-glycosylated.,similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate.,
Gene Name
ANGPTL2 ARP2 UNQ170/PRO196
Protein name
Angiopoietin-related protein 2 (Angiopoietin-like protein 2)
Human protein sequence Database
Q9UKU9
Mouse protein sequence database
Q9R045
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate.
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