Molecular weight (DA)
34kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CPIN1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
cytokine induced apoptosis inhibitor 1(CIAPIN1) Homo sapiens CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008],
Function
function:Probably required during hematopoiesis to mediate antiapoptotic effects of various cytokines. Confers resistance to apoptosis when overexpressed.,miscellaneous:'Ana-mors-in' means 'anti-death molecule' in Latin.,similarity:Belongs to the anamorsin family.,tissue specificity:Ubiquitously expressed. Highly expressed in heart, liver and pancreas.,
Gene Name
CIAPIN1 CUA001 PRO0915
Protein name
Anamorsin (Cytokine-induced apoptosis inhibitor 1) (Fe-S cluster assembly protein DRE2 homolog)
Human protein sequence Database
Q6FI81
Mouse protein sequence database
Q8WTY4
Rat protein sequence database
Q5XID1
Cellular localization
Cytoplasm . Nucleus . Mitochondrion intermembrane space .
Tissue expression
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.
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