Molecular weight (DA)
92kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 250-330
Specificity
SLIK2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes an integral membrane protein that contains two N-terminal leucine-rich repeats domains and contains C-terminal regions similar to neurotrophin receptors. The encoded protein may play a role in modulating neurite activity. Alternatively spliced transcript variants encoding the same protein have been described.[provided by RefSeq, Feb 2010],
Function
function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 14 LRR (leucine-rich) repeats.,tissue specificity:Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, gliobastomas, gangliogliomas and primitive neuroectodermal tumors.,
Gene Name
SLITRK2 CXorf2 KIAA1854 SLITL1 UNQ9197/PRO34756
Protein name
SLIT and NTRK-like protein 2
Fields
>>Cell adhesion molecules
Human protein sequence Database
Q9H156
Mouse protein sequence database
Q810C0
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein . Cell membrane .
Tissue expression
Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.
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