Molecular weight (DA)
47kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 110-190
Specificity
IGS11 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005],
Function
function:Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.,miscellaneous:The last 20 cytoplasmic amino-acids are not required for the cell adhesion function.,PTM:N-glycosylated.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.,
Gene Name
IGSF11 BTIGSF CXADRL1 VSIG3
Protein name
Immunoglobulin superfamily member 11 (IgSF11) (Brain and testis-specific immunoglobulin superfamily protein) (Bt-IGSF) (V-set and immunoglobulin domain-containing protein 3)
Fields
>>Cell adhesion molecules
Human protein sequence Database
Q5DX21
Mouse protein sequence database
P0C673
Rat protein sequence database
Q5U2P2
Cellular localization
Cell membrane ; Single-pass type I membrane protein .
Tissue expression
Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.
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