Molecular weight (DA)
153kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 360-440
Specificity
PTHD2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
developmental stage:Expressed in fetal brain.,similarity:Belongs to the patched family.,similarity:Contains 1 SSD (sterol-sensing) domain.,tissue specificity:Expressed in brain and testis.,
Function
developmental stage:Expressed in fetal brain.,similarity:Belongs to the patched family.,similarity:Contains 1 SSD (sterol-sensing) domain.,tissue specificity:Expressed in brain and testis.,
Gene Name
PTCHD2 DISP3 KIAA1337
Protein name
Patched domain-containing protein 2 (Protein dispatched homolog 3)
Human protein sequence Database
Q9P2K9
Mouse protein sequence database
A3KFU9
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Nucleus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Predominantly localized to cholesterol-enriched domains within the membrane (PubMed:19179482). Localizes to cytoplasmic punctate vesicular structures (By similarity). .
Tissue expression
Expressed in brain and testis (PubMed:15645143).
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