SMD3 Polyclonal Antibody

Polyclonal antibody

Specification

BYab-04975

50UL $180 100UL $255
Delivery： In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host

Reactiveness

Use

Molecular weight (DA)

13kD

Immunogen

Synthesized peptide derived from human protein . at AA range: 30-110

Specificity

SMD3 Polyclonal Antibody detects endogenous levels of protein.

Source

Formulation

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Dilution rate

WB 1:500-2000 ELISA 1:5000-20000

Purification process (Immunogen)

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Background

This gene encodes a core component of the spliceosome, which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Function

disease:In the autoimmune disease systemic lupus erythematosus, antinuclear antibodies are developed with Sm specificity.,PTM:Arg-97 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Methylated on arginine residues by PRMT5 and PRMT7; methylation is required for assembly and biogenesis of snRNPs.,similarity:Belongs to the snRNP core protein family.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE,

Gene Name

SNRPD3

Protein name

Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)

Abbreviation

SMD3

Other name

Fields

>>Spliceosome;>>Systemic lupus erythematosus

Human gene ID

6634

Human protein sequence Database

P62318

Mouse gene ID

Mouse protein sequence database

P62320

Rat gene ID

Rat protein sequence database

Cellular localization

Cytoplasm, cytosol . Nucleus . SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. .

Tissue expression

Lung,

Storage

-20°C/1 year

Experimental scheme>

Procedure

SMD3 Polyclonal Antibody

BYab-04975

Product introduction>

Host

Reactiveness

Use

Molecular weight (DA)

Immunogen

Specificity

Source

Formulation

Dilution rate

Purification process (Immunogen)

Concentration

Background

Function

Gene Name

Protein name

Abbreviation

Other name

Fields

Human gene ID

Human protein sequence Database

Mouse gene ID

Mouse protein sequence database

Rat gene ID

Rat protein sequence database

Cellular localization

Tissue expression

Storage

Experimental scheme>

Citation(0)>

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SMD3 Polyclonal Antibody

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