Molecular weight (DA)
19kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Specificity
MFAP5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha-V-beta-3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
Function
function:Component of the elastin-associated microfibrils.,PTM:Forms intermolecular disulfide bonds either with other MAGP-2 molecules or with other components of the microfibrils.,similarity:Belongs to the MFAP family.,
Protein name
Microfibrillar-associated protein 5 (MFAP-5) (MP25) (Microfibril-associated glycoprotein 2) (MAGP-2)
Human protein sequence Database
Q13361
Mouse protein sequence database
Q9QZJ6
Rat protein sequence database
Cellular localization
Secreted, extracellular space, extracellular matrix.
Tissue expression
Liver,Skeletal muscle,Tongue,Uterus,
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