Molecular weight (DA)
37kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 51-100
Specificity
PGRP3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014],
Function
function:Binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May play a role in innate immunity.,similarity:Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.,subunit:Monomer and dimer.,tissue specificity:Highly expressed in the esophagus, expressed also in tonsils and thymus and to a much lesser extent in the stomach, descending colon, rectum and brain.,
Protein name
Peptidoglycan recognition protein 3 (Peptidoglycan recognition protein I-alpha) (PGLYRPIalpha) (PGRP-I-alpha) (Peptidoglycan recognition protein intermediate alpha)
Human protein sequence Database
Q96LB9
Mouse protein sequence database
A1A547
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Detected in skin epidermis, eccrine sweat glands and ducts, ciliary body epithelial cells of the eye, in small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). Highly expressed in skin and esophagus, expressed also in tonsils and thymus and to a much lesser extent in the stomach, descending colon, rectum and brain.
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