Molecular weight (DA)
33kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 181-230
Specificity
TMM74 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
TMEM74 (Transmembrane Protein 74) is a Protein Coding gene. An important paralog of this gene is TMEM74B. Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction.
Protein name
Transmembrane protein 74
Human protein sequence Database
Q96NL1
Mouse protein sequence database
Q8BQU7
Rat protein sequence database
Cellular localization
Lysosome membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Multi-pass membrane protein .
Tissue expression
Expressed in heart, lung, and placenta.