Molecular weight (DA)
36kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 250-330
Specificity
NPBW1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Found in cerebellum and frontal cortex. Detected at high levels in hipppocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.,
Function
function:Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Found in cerebellum and frontal cortex. Detected at high levels in hipppocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.,
Protein name
Neuropeptides B/W receptor type 1 (G-protein coupled receptor 7)
Fields
>>Neuroactive ligand-receptor interaction
Human protein sequence Database
P48145
Mouse protein sequence database
P49681
Rat protein sequence database
Q56UD9
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.
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