Molecular weight (DA)
43kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 230-310
Specificity
GPR84 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, bone marrow, lung and peripheral blood leukocytes. Within leukocyte population more abundant expression in neutrophils and eosinophils, in comparison with that in T- or B-lymphocytes.,
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, bone marrow, lung and peripheral blood leukocytes. Within leukocyte population more abundant expression in neutrophils and eosinophils, in comparison with that in T- or B-lymphocytes.,
Protein name
G-protein coupled receptor 84 (Inflammation-related G-protein coupled receptor EX33)
Human protein sequence Database
Q9NQS5
Mouse protein sequence database
Q8CIM5
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within the leukocyte population expression is higher in neutrophils and eosinophils relative to T- or B-lymphocytes.
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