Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 280-360
Specificity
MPRB Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation.,similarity:Belongs to the ADIPOR family.,subcellular location:Colocalizes with a lysosomal protein cathepsin D.,tissue specificity:Expressed in brain and spinal cord.,
Function
function:Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation.,similarity:Belongs to the ADIPOR family.,subcellular location:Colocalizes with a lysosomal protein cathepsin D.,tissue specificity:Expressed in brain and spinal cord.,
Gene Name
PAQR8 C6orf33 LMPB1 MPRB
Protein name
Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)
Fields
>>Chemical carcinogenesis - receptor activation
Human protein sequence Database
Q8TEZ7
Mouse protein sequence database
Q80ZE5
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Colocalizes with a lysosomal protein CTSD/cathepsin D. .
Tissue expression
Highly expressed in the hypothalamus (PubMed:23161870). Also expressed in spinal cord, kidney and testis.
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