Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
MGRN1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mahogunin (MGRN1) is a C3HC4 RING-containing protein with E3 ubiquitin ligase activity in vitro.[supplied by OMIM, Apr 2004],
Function
domain:The RING finger is required for ubiquitin ligase activity.,function:Probable E3 ubiquitin-protein ligase.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated in vitro.,similarity:Contains 1 RING-type zinc finger.,
Gene Name
MGRN1 KIAA0544 RNF156
Protein name
E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin RING finger protein 1) (RING finger protein 156)
Fields
>>Ubiquitin mediated proteolysis;>>Hedgehog signaling pathway
Human protein sequence Database
O60291
Mouse protein sequence database
Q9D074
Rat protein sequence database
Q5XIQ4
Cellular localization
Early endosome . The endosomal localization is dependent on the interaction with TSG101.; [Isoform 1]: Cytoplasm, cytosol. Nucleus. Translocation from the cytosol to the nucleus is seen only in the presence of MC1R and MC4R, but not TBXA2R. Excluded from nucleoli.; [Isoform 2]: Cytoplasm, cytosol. Nucleus. Translocation from the cytosol to the nucleus is seen only in the presence of MC1R and MC4R, but not TBXA2R. Excluded from nucleoli.; [Isoform 3]: Cytoplasm, cytosol. Cell membrane.; [Isoform 4]: Cytoplasm, cytosol. Cell membrane.
Tissue expression
Brain,Leukocyte,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车