Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
STAR3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
StAR related lipid transfer domain containing 3(STARD3) Homo sapiens This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],
Function
function:Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain.,similarity:Contains 1 MENTAL domain.,similarity:Contains 1 START domain.,
Gene Name
STARD3 CAB1 MLN64
Protein name
StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3)
Fields
>>Cholesterol metabolism
Human protein sequence Database
Q14849
Mouse protein sequence database
Q61542
Rat protein sequence database
Cellular localization
Late endosome membrane ; Multi-pass membrane protein . Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA, VAPB or MOSPD2. .
Tissue expression
Expressed in retina.
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