Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human PRS55 AA range: 173-223
Specificity
This antibody detects endogenous levels of PRS55 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.24% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The enocoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010],
Function
function:Probable serine protease.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
Gene Name
PRSS55 UNQ9391/PRO34284
Other name
Serine protease 55 (EC 3.4.21.-)
Human protein sequence Database
Q6UWB4
Mouse protein sequence database
Q14BX2
Rat protein sequence database
Cellular localization
[Isoform 1]: Cell membrane ; Lipid-anchor, GPI-anchor . Cytoplasm, cytosol . Mainly found in the membrane part of the cells and only in small amounts in the cytosol. .; [Isoform 2]: Cytoplasm, cytosol . Present primarily in the cytosol and only in minor amounts in the membrane fraction. .
Tissue expression
Only detected in testis. Expressed in spermatogonia, spermatocytes, spermatids, Leydig and Sertoli cells. Expressed in prostate cancer and ovarian cancer (at protein level).
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