Immunogen
Synthesized peptide derived from human SPTCS AA range: 618-668
Specificity
This antibody detects endogenous levels of human SPTCS
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Spatacsin (Colorectal carcinoma-associated protein) (Spastic paraplegia 11 protein)
Fields
>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases
Human protein sequence Database
Q96JI7
Mouse protein sequence database
Q3UHA3
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol . Nucleus . Cell projection, axon . Cell projection, dendrite . Mainly cytoplasmic. .
Tissue expression
Expressed in all structures of brain, with a high expression in cerebellum. Expressed in cortical projection neurons.