Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human SPEB AA range: 266-316
Specificity
This antibody detects endogenous levels of SPEB at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.25% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:Agmatine + H(2)O = putrescine + urea.,cofactor:Manganese .,pathway:Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine (ADC route): step 1/1.,similarity:Belongs to the arginase family. Agmatinase subfamily.,tissue specificity:Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain, testis, skin and the gastrointestinal tract.,
Other name
Agmatinase, mitochondrial (EC 3.5.3.11) (Agmatine ureohydrolase) (AUH)
Fields
>>Arginine and proline metabolism;>>Metabolic pathways
Human protein sequence Database
Q9BSE5
Mouse protein sequence database
A2AS89
Rat protein sequence database
Q0D2L3
Cellular localization
Mitochondrion.
Tissue expression
Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain, testis, skin and the gastrointestinal tract. Within brain, expression is higher in the cerebral cortex with lower levels in the medulla and spinal cord.
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