Molecular weight (DA)
57kD
Immunogen
Synthesized phosho peptide around human Atg13 (Ser355)
Specificity
This antibody detects endogenous levels of Human Atg13 (phospho-Ser355)
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is an autophagy factor and a target of the TOR kinase signaling pathway. The encoded protein is essential for autophagosome formation and mitophagy. [provided by RefSeq, Oct 2016],
Protein name
Atg13 (Ser355)
Other name
Autophagy-related protein 13
Fields
>>Autophagy - other;>>Autophagy - animal;>>Longevity regulating pathway;>>Alzheimer disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases
Human protein sequence Database
O75143
Mouse protein sequence database
Q91YI1
Rat protein sequence database
Cellular localization
Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation. .
Tissue expression
Amygdala,Brain,
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