Molecular weight (DA)
38kD
Immunogen
Synthesized peptide derived from human PLEK2 AA range: 5-55
Specificity
This antibody detects endogenous levels of PLEK2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.38% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015],
Function
function:May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.,similarity:Contains 1 DEP domain.,similarity:Contains 2 PH domains.,
Human protein sequence Database
Q9NYT0
Mouse protein sequence database
Q9WV52
Rat protein sequence database
Cellular localization
Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Tissue expression
Cervix,Ovary,
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