Immunogen
Synthesized peptide derived from human RB11A AA range: 38-88
Specificity
This antibody detects endogenous levels of human RB11A
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Ras-related protein Rab-11A (Rab-11) (YL8)
Fields
>>Endocytosis;>>Endocrine and other factor-regulated calcium reabsorption;>>Vasopressin-regulated water reabsorption;>>Pancreatic secretion;>>Influenza A
Human protein sequence Database
P62491
Mouse protein sequence database
P62492
Rat protein sequence database
P62494
Cellular localization
Cell membrane ; Lipid-anchor . Recycling endosome membrane ; Lipid-anchor . Cleavage furrow . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle membrane . Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (PubMed:11994279). Localizes to the cleavage furrow (PubMed:15601896). Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis (PubMed:20890297). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
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