Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human CTBL1 AA range: 293-343
Specificity
This antibody detects endogenous levels of CTBL1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.107% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013],
Function
function:Induces apoptosis in CHO cells.,tissue specificity:Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.,
Gene Name
CTNNBL1 C20orf33 PP8304
Other name
Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19)
Human protein sequence Database
Q8WYA6
Mouse protein sequence database
Q9CWL8
Rat protein sequence database
Q4V8K2
Cellular localization
[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm .
Tissue expression
Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.
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