Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human DPYL5 AA range: 396-446
Specificity
This antibody detects endogenous levels of DPYL5 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.117% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011],
Function
function:May have a function in neuronal differentiation and/or axon growth.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with other DPYS-like proteins. Interacts with DPYSL2, DPYSL3 and DPYSL4.,
Gene Name
DPYSL5 CRMP5 ULIP6
Other name
Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6)
Human protein sequence Database
Q9BPU6
Mouse protein sequence database
Q9EQF6
Rat protein sequence database
Q9JHU0
Cellular localization
Cytoplasm .
Tissue expression
Amygdala,Brain,Cajal-Retzius cell,Fetal brain cortex,Lung,Spinal cord,
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