Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human PGM5 AA range: 357-407
Specificity
This antibody detects endogenous levels of PGM5 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.145% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995 [PubMed 8586438]).[supplied by OMIM, Mar 2008],
Function
cofactor:Binds 1 magnesium ion per subunit .,function:Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity.,similarity:Belongs to the phosphohexose mutase family.,subcellular location:Adherens-type cellular junctions.,subunit:Interacts with cytoskeletal proteins dystrophin and utrophin.,tissue specificity:Expressed in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component.,
Other name
Phosphoglucomutase-like protein 5 (Aciculin) (Phosphoglucomutase-related protein) (PGM-RP)
Human protein sequence Database
Q15124
Mouse protein sequence database
Q8BZF8
Rat protein sequence database
Cellular localization
Cell junction, adherens junction . Cytoplasm, cytoskeleton . Cell membrane, sarcolemma . Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments. .
Tissue expression
Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver, kidney, skin and brain (at protein level).
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车