Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human TAPT1 AA range: 295-345
Specificity
This antibody detects endogenous levels of TAPT1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.149% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined. [provided by RefSeq, Jul 2008],
Function
function:May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). In case of infection, may act as a fusion receptor for cytomegalovirus (HCMV) strain AD169.,similarity:Belongs to the TAPT1 family.,
Other name
Transmembrane anterior posterior transformation protein 1 homolog (Cytomegalovirus partial fusion receptor)
Human protein sequence Database
Q6NXT6
Mouse protein sequence database
Q4VBD2
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body . Membrane ; Multi-pass membrane protein .
Tissue expression
Embryo,Lung,Testis,
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