Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from human S13A5 AA range: 313-363
Specificity
This antibody detects endogenous levels of S13A5 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.157% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],
Function
function:High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.,similarity:Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily.,tissue specificity:Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.,
Other name
Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter)
Human protein sequence Database
Q86YT5
Mouse protein sequence database
Q67BT3
Rat protein sequence database
Q8CJ44
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis.
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