Immunogen
Synthesized peptide derived from human EVX2 AA range: 138-188
Specificity
This antibody detects endogenous levels of EVX2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009],
Function
developmental stage:Expressed during early embryogenesis and neurogenesis in a biphasic manner.,similarity:Belongs to the even-skipped homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Human protein sequence Database
Q03828
Mouse protein sequence database
P49749
Rat protein sequence database
Cellular localization
Nucleus.
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