Molecular weight (DA)
105kD
Immunogen
Synthesized peptide derived from human HAUS6 AA range: 476-526
Specificity
This antibody detects endogenous levels of HAUS6 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.236% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012],
Gene Name
HAUS6 DGT6 FAM29A KIAA1574
Other name
HAUS augmin-like complex subunit 6
Human protein sequence Database
Q7Z4H7
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes to interphase centrosomes and to mitotic spindle microtubules. .
Tissue expression
Lung,PCR rescued clones,Uterus,
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