Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from human PATL1 AA range: 263-313
Specificity
This antibody detects endogenous levels of PATL1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.335% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Required for P body formation.,similarity:Belongs to the PAT1 family.,tissue specificity:Ubiquitous.,
Gene Name
PATL1 OK/KNS-cl.5
Other name
Protein PAT1 homolog 1 (PAT1-like protein 1) (Protein PAT1 homolog b) (Pat1b) (hPat1b)
Human protein sequence Database
Q86TB9
Mouse protein sequence database
Q3TC46
Rat protein sequence database
B5DF93
Cellular localization
Cytoplasm, P-body . Nucleus . Nucleus, PML body . Nucleus speckle . Predominantly cytoplasmic (PubMed:22090346). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner (PubMed:22090346). Enriched in splicing speckles. Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus (PubMed:22090346). .
Tissue expression
Ubiquitous.
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