Immunogen
Synthesized peptide derived from human GMPPA AA range: 184-234
Specificity
This antibody detects endogenous levels of GMPPA at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is thought to encode a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides. [provided by RefSeq, Jul 2008],
Function
catalytic activity:GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose.,pathway:Protein modification; protein glycosylation.,sequence caution:Originally thought to be a fragment.,similarity:Belongs to the transferase hexapeptide repeat family.,
Fields
>>Fructose and mannose metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of cofactors;>>Biosynthesis of nucleotide sugars
Human protein sequence Database
Q96IJ6
Mouse protein sequence database
Q922H4
Rat protein sequence database
Q5XIC1
Cellular localization
Cytoplasm . Myc-tagged GMPPA shows a diffuse cytoplasmic and nuclear pattern in transfected COS-7 cells.
Tissue expression
Expressed in fibroblasts (at protein level).
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