Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from human LRFN1 AA range: 529-579
Specificity
This antibody detects endogenous levels of LRFN1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.339% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Involved in the regulation of excitatory synapses.,PTM:Glycosylated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the LRFN family.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1, DLGAP1, AMPA receptors and NMDA receptors (By similarity). Interacts with DLG4.,
Gene Name
LRFN1 KIAA1484 SALM2
Other name
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2)
Human protein sequence Database
Q9P244
Mouse protein sequence database
Q2WF71
Rat protein sequence database
P0C7J6
Cellular localization
Membrane ; Single-pass type I membrane protein . Cell junction, synapse . Cell junction, synapse, postsynaptic density membrane . Detected in excitatory, but not inhibitory, synaptic plasma membrane. .
Tissue expression
Brain,Ovary,Uterus,
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