Immunogen
Synthesized peptide derived from human OZF AA range: 3-53
Specificity
This antibody detects endogenous levels of OZF at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
miscellaneous:Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.,PTM:Sumoylated.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 10 C2H2-type zinc fingers.,subunit:Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP.,tissue specificity:Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney.,
Human protein sequence Database
Q15072
Mouse protein sequence database
Q8BQN6
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers.
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