Immunogen
Synthesized peptide derived from human MTCH2 AA range: 59-109
Specificity
This antibody detects endogenous levels of MTCH2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015],
Function
function:The substrate transported is not yet known. Induces mitochondrial depolarization.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 2 Solcar repeats.,
Gene Name
MTCH2 MIMP HSPC032
Human protein sequence Database
Q9Y6C9
Mouse protein sequence database
Q791V5
Rat protein sequence database
Cellular localization
Mitochondrion outer membrane ; Multi-pass membrane protein .
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