Immunogen
Synthesized peptide derived from human SARAF AA range: 277-327
Specificity
This antibody detects endogenous levels of SARAF at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
similarity:Belongs to the TMEM66 family.,tissue specificity:Highly expressed in macrophages.,
Gene Name
TMEM66 SARAF XTP3 HSPC035 NPD003 PSEC0019 UNQ1967/PRO4499
Human protein sequence Database
Q96BY9
Mouse protein sequence database
Q8R3Q0
Rat protein sequence database
Q6AYN2
Cellular localization
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Translocates to the endoplasmic reticulum-plasma membrane (ER-PM) region in a STIM1-dependent manner following cytosolic Ca(2+) elevation.; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Tissue expression
Highly expressed in macrophages.