Immunogen
Synthesized peptide derived from human WASH1 AA range: 163-213
Specificity
This antibody detects endogenous levels of WASH1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
miscellaneous:The telomeric region of chromosome 9p is paralogous to the pericentromeric regions of chromosome 9 as well as to 2q. Paralogous regions contain 7 transcriptional units, including CXYorf1. Duplicated CXYorf1 genes are also present in the Xq/Yq pseudoautosomal region, as well as on chromosome 1 and 15. The chromosome 16 copy seems to be a pseudogene.,similarity:Belongs to the FAM39 family.,similarity:Contains 1 WH2 domain.,
Human protein sequence Database
A8K0Z3
Mouse protein sequence database
Q8VDD8
Rat protein sequence database
B2RYF7
Cellular localization
Early endosome membrane . Recycling endosome membrane . Late endosome . Cytoplasmic vesicle, autophagosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localization to the endosome membrane is mediated via its interaction with WASHC2 (PubMed:19922874). Localizes to MMP14-positive late endosomes and transiently to invadipodia (PubMed:24344185). Localized to Salmonella typhimurium entry sites (By similarity). .
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