Immunogen
Synthesized peptide derived from human CL16A AA range: 129-179
Specificity
This antibody detects endogenous levels of CL16A at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
Function
disease:Defects in CLEC16A might be a cause of insulin-dependent diabetes mellitus (IDDM) [MIM:222100].,similarity:Belongs to the CLEC16A/gop-1 family.,tissue specificity:Almost exclusively expressed in immune cells, including dendritic cells, B lymphocytes and natural killer cells.,
Gene Name
CLEC16A KIAA0350
Human protein sequence Database
Q2KHT3
Mouse protein sequence database
Q80U30
Rat protein sequence database
Cellular localization
Endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Associates with the endolysosome membrane. .
Tissue expression
Almost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells.
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