Immunogen
Synthesized peptide derived from human FKB11 AA range: 58-108
Specificity
This antibody detects endogenous levels of FKB11 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008],
Function
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:PPIases accelerate the folding of proteins during protein synthesis.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 1 PPIase FKBP-type domain.,
Gene Name
FKBP11 FKBP19 UNQ336/PRO535
Human protein sequence Database
Q9NYL4
Mouse protein sequence database
Q9D1M7
Rat protein sequence database
Cellular localization
Membrane ; Single-pass membrane protein .
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