Immunogen
Synthesized peptide derived from human T132E AA range: 486-536
Specificity
This antibody detects endogenous levels of T132E at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
disease:TMEM132E gene is identified as one gene located in a region involved in a heterozygous deletion of approximately 4.7 Mb; this deletion, involving the NF1 gene and contiguous genes lying in its flanking regions, is observed in one patient with NF1 and 17q11.2 microdeletion syndrome [MIM:162200]. The NF1 microdeletion syndrome is often characterized by a more severe phenotype than that observed in the majority of NF1 patients. Indeed, patients with NF1 microdeletion often show variable facial dysmorphism, mental retardation, developmental delay, and an excessive number of neurofibromas.,similarity:Belongs to the TMEM132 family.,
Human protein sequence Database
Q6IEE7
Mouse protein sequence database
Q6IEE6
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein .
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