Immunogen
Synthesized peptide derived from human B4GN4 AA range: 498-548
Specificity
This antibody detects endogenous levels of B4GN4 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.,function:Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.,online information:GlycoGene database,similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family.,tissue specificity:Highly expressed in ovary, adult and fetal brain. Also expressed in fetal kidney and lung.,
Fields
>>Various types of N-glycan biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q76KP1
Mouse protein sequence database
Q766D5
Rat protein sequence database
Cellular localization
Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein .
Tissue expression
Highly expressed in ovary, adult and fetal brain. Also expressed in fetal kidney and lung.