Immunogen
Synthesized peptide derived from human U17L6 AA range: 207-257
Specificity
This antibody detects endogenous levels of U17L6 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,caution:The RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17. It is present with an interindividual variation in copy number and between 20 to 103 copies can be found in the genome both on chromosome 4 and chromosome 8.,function:Seems to be non-functional in the regulation of apoptosis. Cleaves ubiquitin fusion protein substrates.,similarity:Belongs to the peptidase C19 family. USP17 subfamily.,
Gene Name
USP17L6 USP17C USP17D USP17N
Human protein sequence Database
Q6QN14
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm .