Immunogen
Synthesized peptide derived from human KR511 AA range: 49-99
Specificity
This antibody detects endogenous levels of KR511 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 5 family.,subunit:Interacts with hair keratins.,tissue specificity:Restricted to hair root, not detected in any other tissues.,
Gene Name
KRTAP5-11 KAP5.11 KRTAP5.11
Human protein sequence Database
Q6L8G4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
keratin filament,
Tissue expression
Restricted to hair root, not detected in any other tissues.