Immunogen
Synthesized peptide derived from human DMBX1 AA range: 88-138
Specificity
This antibody detects endogenous levels of DMBX1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Function
function:Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,subunit:Homodimer or heterodimer. Forms heterodimers with OTX2.,
Gene Name
DMBX1 MBX OTX3 PAXB
Human protein sequence Database
Q8NFW5
Mouse protein sequence database
Q91ZK4
Rat protein sequence database
Cellular localization
Nucleus .
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