Immunogen
Synthesized peptide derived from human PTBP3 AA range: 103-153
Specificity
This antibody detects endogenous levels of PTBP3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Function
function:May play a role in regulation of differentiation. In vitro, binds RNA, preferentially to both poly(G) and poly(U). Overexpressed, blocks differentiation of K562 leukemia cells following treatment with phorbol esters or sodium butyrate without affecting proliferation.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Expressed in several hematopoietic cell lines examined.,
Human protein sequence Database
O95758
Mouse protein sequence database
Q8BHD7
Rat protein sequence database
Q9Z118
Cellular localization
nucleus,
Tissue expression
Expressed in several hematopoietic cell lines examined.
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