Immunogen
Synthesized peptide derived from human PIGU AA range: 313-363
Specificity
This antibody detects endogenous levels of PIGU at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Cdc91, a predicted integral membrane protein that may function in cell division control. The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. [provided by RefSeq, Jul 2008],
Function
function:Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGU family.,subunit:Forms a complex with PIGK/GPI8, PIGS, PIGT and GPAA1/GAA1.,
Gene Name
PIGU CDC91L1 PSEC0205 UNQ3055/PRO9875
Fields
>>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q9H490
Mouse protein sequence database
Q8K358
Rat protein sequence database
Q8CHJ1
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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