Immunogen
Synthesized peptide derived from human MBOA7 AA range: 293-343
Specificity
This antibody detects endogenous levels of MBOA7 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009],
Function
catalytic activity:Acyl-CoA + 1-acyl-sn-glycero-3-phosphatidylinositol = CoA + 1,2-diacyl-sn-glycero-3-phosphatidylinositol.,enzyme regulation:Activity is inhibited by thimerosal.,function:Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.,pathway:Lipid metabolism; phospholipid metabolism.,similarity:Belongs to the membrane-bound acyltransferase family.,tissue specificity:Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium.,
Gene Name
MBOAT7 BB1 LENG4 OACT7
Fields
>>Glycerophospholipid metabolism
Human protein sequence Database
Q96N66
Mouse protein sequence database
Q8CHK3
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Localized in specific membrane structures termed mitochondria-associated membranes (MAMs) which connect the endoplasmic reticulum (ER) and the mitochondria. .
Tissue expression
Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium and urothelium.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车