Immunogen
Synthesized peptide derived from human B3GN8 AA range: 218-268
Specificity
This antibody detects endogenous levels of B3GN8 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans.,induction:Up-regulated in colon cancer.,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,subunit:Forms a complex of enhanced enzymatic activity with B3GNT2 in vitro.,tissue specificity:Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines.,
Gene Name
B3GNT8 B3GALT7 BGALT15
Human protein sequence Database
Q7Z7M8
Mouse protein sequence database
Q8R3I9
Rat protein sequence database
Cellular localization
Golgi apparatus membrane ; Single-pass type II membrane protein .
Tissue expression
Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines.
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